>16 Month Journey

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This is our biomedical journey in the past 16 months – please see below for list of supplements that were added on as the months went by and the steps we took with our little girl.


June 2008 – Maya was diagnosed with mild to moderate Autism at 2 years 8 months. Implemented GFCF diet. Able to make occassional 1 word request within 1 week.

July – December 2008 – started home based ABA at 6 hours a week. Eventually this grew into 18 hours a week maximum by December. GFCF diet was refined over the next 6 months, but still included soy. Maya was able to make occassional 2 word request, less hyper and better mood. No other biomed intervention except GFCF diet.

January 2009 – Hospitalised with Rotavirus. Started center-based ABA for 30 hours per week. Change to rice milk, started Super Nu Thera, probiotics and Cod Liver Oil.

February – March 2009 – consulted with Dr Sundardas, he only required us to do hair analysis. Started calcium, zinc, 3 Billion CFU non-refrigerated probiotic, Nordic Naturals cod liver oil, Efalex, Intestamine, NTC Detox, Zeolite, digestive enzymes, ASD Plex, Super Nu Thera. Implemented the Blood Type Diet as per recommendation. After 2 1/2 months on his protocol and despite my insistence that we do more to address Maya’s unresolved gut issues, Dr S recommended we start on B12 shots instead. So we decided to change to another doctor as I feel that there were gaps in treatment for gut issues. Atec score of 78

April 2009 – consulted with Dr Erwin Kay. Asked us to do OATs, IgG and Comprehensive Stool Test. Dr Erwin accepted the previous hair test result. Revert back to basic GFCF diet, started supplements based on basic gut treatment with prebiotic, multi-species probiotic, lactobaccilus probiotic, melatonin, l-glutamine (for leaky gut, but later had to stop because of bad regression), super nu thera, cod liver oil.


May 09 – added on taurine, digestive enzyme, phenol assist, glutathione lotion, 1 month course of anti-fungal Diflucan, epsom salt bath, n-acetyl cysteine, zinc. Changed to organic food.


June 09 – started 2 week course of Cedax antibiotic, rotate probiotics to Kirkman’s Probio Gold, 2nd course of Fluconazole antifungal, added calcium/magnesium combo, vitamin C, vitamin E, Methyl B12 (every 2 days, adjusted dosage for next 1 month) and Ketaconazole cream for her itchy and flaky feet (2-3 weeks only). Replaced old carpeting and air conditioning in the girls’ bedroom. Removed all dust-collecting and mold-producing items and installed an air purifier.


July 09 – added on Interfase, sodium butyrate, MSM glucosamin cream, AminoPlex (all these 4 based on Dr Westaway’s consult and monitored by Dr Erwin. Eventually had to stop AminoPlex due to regression) more readjustment of dosage for existing supplements. Added Dual Detox and Valtrex anti-viral (eventually we had to give up on Valtrex because we couldn’t get Maya to take it), 2 month course of Nystatin, Candex, increase magnesium, s.boulardii, OSR (upon Dr Westaway’s consult, but product ordered and approved by Dr Erwin). Replaced all non-stick cookware, reduce microwave use and plastics.


August 09- We did additional tests for Essential Fatty Acids, Plasma Amino Acid and kidney and liver function. Changed to Zinc picolinate and Ester C (based on Dr Rina’s consult), change to separate Calcium and magnesium (not combined), magnesium sulfate cream, 2nd course of Cedax antibiotic, another course of Fluconazole (both girls at this time had recurring gastro issues with bacterial infections and colds & flu), change MB12 to daily shots, rotate probiotics to Klaire Labs Therbiotic complete. Only use organic and chemical free cleaning products for household cleaning as well as body care including shampoo and soaps.


September 09 – Added Culturelle and increased probiotics due to last month’s infections, gut issues and antibiotic use. Increase MB12 to 0.05, change from SNT to B6 P-5-P, change to Magnesium glycinate powder, rotate digestive enzyme with Trienza, added ViraStop, SAMe200, Folate Acid, and adjustment of supplements based on new test results. Psychological assesment shows great improvement across the board, Atec scores down to 30 from previous 78 in April 2009.


October 09 – Maya turns 4 years old. Added TMG (upon Dr Anthony Underwood’s consult), readjust MB12 to alternate days, change from Candex to Candidase, increase ViraStop dosage (very little change due to Dr Erwin being away) Replaced all milk bottles to BPA free.


Who knows what next month will bring. It is undeniable that Maya’s progress has been on fast track ever since we had Dr Erwin to guide us, we couldn’t have gotten this far without him.

>B12

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Vitamin B12 therapy is one of the most popular treatments in Autism biomedical intervention. B12 is utilized in almost every cell in the human body, it affects the normal functioning of the nervous system, the detoxification system and other biomedical pathways. Most parents report almost immediate improvements once starting B12 therapy. To read more about the benefits of B12, please refer to the article at this link http://www.talkaboutcuringautism.org/medical/methyl-b12-treatments.htm
You can also watch videos by doctors and parents on how to administer methyl B12 shots. Just do a search on Google or YouTube for Autism B12 Injections and you will find many videos. Your doctor will also teach you how to do the shot, Paul and I also practiced injecting into an apple before we did it for the first time on Maya.
We saw huge gains in maya’s language and cognition and overall behavior. 7-8 word sentences are used frequently. Maya now strings 2-3 sentences together. She easily follows 2 step instructions. She is able to answer questions that she previously could not understand eg. “What did you do at school today?” and “Who did you play with?” . She makes new requests such as “Mummy, can you turn on the lights please”. She asks us questions like “Daddy, what are you doing?” Also, “No, I don’t want to go to school. Let’s go to the zoo!”. Her behavior is more appropriate and we saw improvements in her social skills.
There are many forms of administering B12 – oral, transdermal, nasal or subcutaneous injections. Most of our children have issues with malabsorption, therefor oral types such as capsules and lollipops may not be the best option. Yes, lollipop version of B12 – Stan Kurtz created a lollipop called Revita Pops. You may need to check with the website on where to purchase them. Check out www.revitapop.com
There is also several types of MB12 Nasal Spray, however this may not be well accepted for younger children. Transdermal B12 may take the form of creams or patches.
According to research and parents’ feedback, the most effective form of administering B12 are injections. For injections, the methylated version of B12 is used, thus usually referred to as Methyl B12. It is also known as Methycobalamin. Subcutaneous injections requires thin and short needles, the shots are very shallow, usually on the upper outer quadrant of the buttocks and taken at an angle of 30 degrees or less. Because the shot is given just under the skin, you don’t penetrate it into deep fat tissue or muscle tissue, it doesn’t get into a vein, a nerve or artery.
Depending on your child’s weight, the doctor will usually prescribe 0.03mls per shot. It’s a very tiny amount. Frequency will vary according to doctor and child, usually every 3 days. You have a choice of either getting the B12 in a multiple-dose container or prefilled syringes. Your doctor can order both from a compounding pharmacy. You will need to store methyl B12 in the refrigerator and keep it away from the light.
Multiple-dose container – A single vial may last you 2 months or more depending on your dosage and frequency. It’s more affordable compared to pre-filled syringes. You will need to wrap the vial in aluminum foil in order to protect it from the light. Also, if you find that the dosage recommended by the doctor doesn’t seem to be effective, you can adjust the amount easily. However you will need to purchase your own syringes and fill it up yourself. Dr Erwin Kay sells methyl B12 at SGD$180 per 3ml vial. You can purchase BD Ultra-Fine Insulin Syringe 1/2cc at any pharmacy in Malaysia, a pack of 10 syringes are RM5-10. These needles are the same size ultra-fine, however at 1/2″ it is slightly longer than pre-filled syringes. You just have to exercise more control during the injection to make sure the needle doesn’t go in deeper.
Pre-filled syringes – this reduces the hassle of filling up the syringes yourself every time. It’s very convenient and you know the dosage is correct. However there are 2 drawbacks; firstly it is a lot more expensive – 1 pre-filled syringe may cost SGD$10.00 – SGD$20.00 each. Depending on which compounding pharmacy and the US$ currency exchange. Your DAN doctor can give you the exact figure.
Depending on how often your doctor recommends you to do it, the cost can be very high. Secondly, because it is pre-filled, you may not be able to adjust the amount of B12. The needles are ultra-fine and best of all, the needle length is 1/4″. This is the perfect depth for subcutaneous injections and you are assured that it will never go in too deep.
We have been giving Maya methyl B12 shots for 2 months. For the first 1 month, we did it every other day. Dr Erwin initially prescribed 0.03mls however we did not see any improvements within 1 week. He then advised us to increase the dosage to 0.04mls and we saw amazing improvements within 1 hour! We now give maya methyl B12 injections 0.04mls every day. We did not get pre-filled syringes, instead ours came in a vial.
At SGD$180 a vial, for 0.04mls every day, I calculate our cost to be RM200 per month for B12 therapy including the cost of the B12 3ml vial and syringes. Definitely worth the money and the initial struggles.
Initially it was very hard, Paul would hold Maya tightly and she would be screaming and fighting and wriggling and kicking, whilst I’m trying to inject her at the proper angle, at the proper spot at the shallowest depth possible. Maya would start screaming and struggling the moment I swabbed her bottom with the pre-injection swabs. The injection itself is very quick and I try to find interesting plasters or band-aids. She would then cry for 10 minutes while we comforted her and redirect her.
Eventually, the cries got less and less and for the past 1 month, Paul doesn’t even have to hold her and she doesn’t cry at all anymore. I tell Maya “It’s time for Doctor Mummy” and she’ll bend over the bed willingly and will keep still while I give her the shot. Usually we have a discussion about what plasters she’ll get today, her favorites are the Disney princess ones:-) The whole process takes less than 1 minute.
To save time, I usually fill up to 10 syringes at once and cover the needle with the needle shield. Then I make a little parcel made of aluminium foil. In every piece of foil, I place 1 syringe that I’ve pre-filled to the correct dosage, 1 swab, 1 cotton ball and 1 plaster. And I roll up everything together making sure that the plunger is well protected and not going to be accidently pressed. And everyday I just grab a parcel from the refrigerator so it’s quick and easy. And that’s how I make my own pre-filled pre-prepared B12 shots.
Depending on your child’s underlying medical issues and personal preference, you can talk to your DAN doctor about which forms of B12 are best for your child.